Rams vs Colts live updates, stats, results, highlights today NFL Week 4

The Indianapolis Colts try to remain unbeaten when they visit the Los Angeles Rams in NFL Week 4 action. Three Colts starters are out with injuries; Rams wide receiver Davante Adams (hamstring) is available.

The Colts have won two blowouts and with a walk-off field goal. The Rams beat two AFC South teams before squandering a 19-point lead against the Eagles in Philadelphia.

We will have score updates and highlights throughout, so please remember to refresh.

Colts score vs. Rams: Spencer Shrader adds a field goal

Colts 20, Rams 13, 8:58 left 4Q: Spencer Shrader connects from 38 yards. Tyler Warren is called for pass interference on the first play of the drive.

Mike Hilton forces a Rams turnover

11:22 left 4Q: New Colts signee Mike Hilton hits Rams running back Kyren Williams, and the Colts recover at the Rams' 17.

Colts score vs. Rams: Michael Pittman Jr.'s touchdown puts the Colts ahead

Colts 17, Rams 13, 11:34 left 4Q: Daniel Jones hits Michael Pittman Jr. from 2 yards. That completes an 11-play, 90-yard drive that takes 6:07.

Colts score vs. Rams: Teams are trading punts

2:41 left 3Q: The Colts are starting at their 10 after a Rams punt, their fourth of the quarter. The Colts have punted twice in the quarter.

Colts score vs. Rams: Adonai Mitchell fumbles the ball out of the end zone

11:32 left 3Q: Adonai Mitchell loses the ball just before the end zone, and it rolls out the back. Rams ball and the Colts lose a 76-yard go-ahead touchdown.

Colts score vs. Rams: Los Angeles leads 13-10 at halftime

Daniel Jones is 10-of-14 for 85 yards and an early interception. Tyler Warren has 3 catches for 30 yards and a rushing touchdown. Jonathan Taylor has just 5 carries for 25 yards.

Matthew Stafford is 16-of-24 for 174 yards and a late touchdown to Davante Adams. Puka Nacua has 7 catches for 112 yards. Kyren Williams has 7 carries for 55 yards. Joshua Karty has 2 field goals.

The Rams get the kickoff to start the second half.

Colts score vs. Rams: Davante Adams scores a touchdown

Rams 13, Colts 10, :07 left 2Q: Matthew Stafford hits Davante Adams for a 10-yard score to complete a 96-yard drive. Laiatu Latu sacks Matthew Stafford. The Rams complete passes to Puka Nacua and Davante Adams to reach Colts territory.

Laiatu Latu gets involved with a sack of Matthew Stafford

Colts score vs. Rams: Rigoberto Sanchez punts

2:14 left 2Q: The Colts pin the Rams at the 4. This is the first game the Colts have punted and committed a turnover.

Colts score vs. Rams: Joshua Karty adds another field goal

Colts 10, Rams 6, 5:21 left 2Q: Joshua Karty connects from 37 yards. Under pressure, Matthew Stafford drops in a 31-yard completion to Puka Nacua into the red zone.

Colts score vs. Rams: Tyler Warren rushes for a touchdown

Colts 10, Rams 3, 12:17 left 2Q: Tyler Warren rushes in from 2 yards on 4th down. Something of a fullback play.

Colts stop Rams quarterback Matthew Stafford on 4th down play

2:02 left 1Q: The Colts stuff Rams quarterback Matthew Stafford and take over at L.A.'s 45-yard line.

Colts score vs. Rams: Spencer Shrader makes a 52-yard field goal

Colts 3, Rams 3, 4:55 left 1Q: The Colts commit consecutive penalties costing them 25 yards. Tyler Warren has 2 catches for 29 yards on the drive. Anthony Gould starts the drive with a 38-yard kickoff return.

Colts score vs. Rams: Joshua Karty kicks a field goal for L.A.

Rams 3, Colts 0, 7:32 left 1Q: Joshua Karty kicks a 42-yard field goal. The drive is 11 plays and 57 yards.

Daniel Jones throws first interception of the season

12:39 left 1Q: Daniel Jones underthrows A.D. Mitchell, and Kam Curl intercepts. L.A. takes over at its 20. That's the Colts' first turnover this season.

What time does Los Angeles Rams-Indianapolis Colts game start today, Sunday, Sept. 28, 2025? When is Colts-Rams NFL football game tonight?

The Indianapolis Colts and Los Angeles Rams will play at 4:05 p.m. ET Sunday, Sept. 28, 2025.

Watch Colts-Rams NFL Week 4 action with Fubo

What channel is Indianapolis Colts vs Los Angeles Rams game on TV today, Sunday, Sept. 28, 2025? How to watch NFL Week 4 football game tonight live

The Indianapolis Colts and Los Angeles Rams will air on Fox at 4:05 p.m. ET Sunday, Sept. 28, 2025.

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How to stream Rams vs Colts NFL football game today, Sunday, Sept. 28, 2025. Where to watch Colts-Rams Week 4 game tonight

The Indianapolis Colts and Los Angeles Rams will stream on NFL+ at 4:05 p.m. ET Sunday, Sept. 28, 2025. Fans can download NFL+ in the Apple App Store or on Google Play.

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Are the Indianapolis Colts favored vs. the Los Angeles Rams on Sunday, Sept. 28? Los Angeles Rams vs. Indianapolis Colts betting odds for NFL Week 4 on Sunday, Sept. 28

via BetMGM

Favorite: Rams by 3.5 points

Over/under: 49.5 total points

Moneyline: Colts +155, Rams -190

ESPN's matchup predictor gives the Rams a 55.5% chance of winning.

NFL schedule Week 4

(all times ET)

Thursday, Sept. 25: Seattle Seahawks 23, Arizona Cardinals 20, (summary, box score)

Sunday, Sept. 28: Minnesota Vikings vs. Pittsburgh Steelers in Dublin, 9:30 a.m., NFL Network (summary, box score)

Sunday, Sept. 28: Washington Commanders at Atlanta Falcons, 1 p.m., CBS (summary, box score)

Sunday, Sept. 28: New Orleans Saints at Buffalo Bills, 1 p.m., CBS (summary, box score)

Sunday, Sept. 28: Cleveland Browns at Detroit Lions, 1 p.m., Fox (summary, box score)

Sunday, Sept. 28: Tennessee Titans at Houston Texans, 1 p.m., CBS (summary, box score)

Sunday, Sept. 28: Carolina Panthers at New England Patriots, 1 p.m., Fox (summary, box score)

Sunday, Sept. 28: Los Angeles Chargers at New York Giants, 1 p.m., CBS (summary, box score)

Sunday, Sept. 28: Philadelphia Eagles at Tampa Bay Buccaneers, 1 p.m., Fox (summary, box score)

Sunday, Sept. 28: Indianapolis Colts at Los Angeles Rams, 4:05 p.m., Fox (summary, box score)

Sunday, Sept. 28: Jacksonville Jaguars at San Francisco 49ers, 4:05 p.m., Fox (summary, box score)

Sunday, Sept. 28: Baltimore Ravens at Kansas City Chiefs, 4:25 p.m., CBS (summary, box score)

Sunday, Sept. 28: Chicago Bears at Las Vegas Raiders, 4:25 p.m., CBS (summary, box score)

Sunday, Sept. 28: Green Bay Packers at Dallas Cowboys, 8:20 p.m., NBC, Peacock, Telemundo (summary, box score)

Monday, Sept. 29: New York Jets at Miami Dolphins, 7:15 p.m., ESPN (summary, box score)

Monday, Sept. 29: Cincinnati Bengals at Denver Broncos, 8:15 p.m., ABC (summary, box score)

Colts 2025 regular-season schedule, results

Week 1: Indianapolis Colts 33, Miami Dolphins 8, box score, stats

Week 2: Colts 29, Denver Broncos 28, box score, stats

Week 3: Colts 41, Tennessee Titans 20, box score, stats

Week 4: Sunday, Sept. 28, at Los Angeles Rams, 4:05 p.m., Fox

Week 5: Sunday, Oct. 5, vs. Las Vegas Raiders, 1 p.m., Fox

Week 6: Sunday, Oct. 12, vs. Arizona Cardinals, 1 p.m., Fox

Week 7: Sunday, Oct. 19, at Los Angeles Chargers, 4:05 p.m., CBS

Week 8: Sunday, Oct. 26, vs. Tennessee Titans, 4:25 p.m., CBS

Week 9: Sunday, Nov. 2, at Pittsburgh Steelers, 1 p.m., CBS

Week 10: Sunday, Nov. 9, vs. Atlanta Falcons in Berlin, Germany, 9:30 a.m., NFL Network

Week 11: Bye

Week 12: Sunday, Nov. 23, at Kansas City Chiefs, 1 p.m., CBS

Week 13: Sunday, Nov. 30, vs. Houston Texans, 1 p.m., CBS

Week 14: Sunday, Dec. 7, at Jacksonville Jaguars, 1 p.m., CBS

Week 15: Sunday, Dec. 14, at Seattle Seahawks, 4:25 p.m., CBS

Week 16: Monday, Dec. 22, vs. San Francisco 49ers, 8:15 p.m., ESPN's "Monday Night Football"

Week 17: Sunday, Dec. 28, vs. Jacksonville Jaguars, 1 p.m., Fox

Week 18: Date TBD, at Houston Texans, time TBD, TBD

Joel A. Erickson covers the Colts all season. Get more coverage on IndyStarTV and with the Colts Insider newsletter.

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