We came out of Week 4 with Malik Nabers (knee) and Tyreek Hill (knee) lost for the season. Trey Benson (knee) was placed on injured reserve, and Lamar Jackson (hamstring) is expected to miss several weeks. And, as of Wednesday, we're waiting to find out the status of Bucky Irving (foot) and Chuba Hubbard (calf).This all comes with four teams on a bye in Week 5 (Atlanta, Chicago, Green Bay, and Pittsburgh). Are you having fun setting your lineups?Now, when injuries occur, it gives other players the chance to step up. So we'll see what happens for prominent guys like Jaylen Waddle, along with unproven commodities like Michael Carter, who have the chance to thrive in expanded roles.We'll address all of these scenarios and more below. Hopefully, your teams still have enough quality players to compete at a high level in Week 5. Or, maybe you'll get lucky, and someone like Darius Slayton can be your savior and lead you to a victory this week.START 'EM & SIT 'EMQuarterbacksSTART 'EM & SIT 'EMRunning BacksSTART 'EM & SIT 'EMWide ReceiversSTART 'EM & SIT 'EMTight EndSTART 'EM & SIT 'EMDSTCardinals (vs. TEN)The Titans were just shut out by the Texans in Week 4, and Tennessee has allowed at least four sacks in three games this season. Cam Ward has an interception in each of his past two games against Indianapolis and Houston, and the Cardinals are allowing just 18.5 points per game on defense. I like the Cardinals DST a lot in Week 5.Browns (vs . MIN)Chiefs (at JAC)Giants (at NO)Broncos (vs. PHI)It's tough to sit the Broncos DST in the majority of leagues, but the matchup against the Eagles isn't favorable. Philadelphia has scored at least 31 points in each of the past two games against the Rams and Buccaneers, and the Eagles have one turnover on the season. Jalen Hurts has also been sacked just nine times. While this could be a low-scoring game, I don't expect the Broncos DST to create many turnovers or sacks, so I don't consider the unit a No. 1 Fantasy option in Week 5.
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